A 32 year old Asian female on 300 mg per day of phenytoin following meningioma excision developed a fever with a diffuse maculopapular rash, lymphadenopathy and splenomegaly after12 days.A diagnosis of DRESS (Drug Rash Eosinophilia and Systemic Symptoms) syndrome was made.Patient was started on prednisolone at a dose of 1 mg/kg but since there was
Recommendations for the classification of germline variants in the exonuclease domain of POLE and POLD1
Abstract Background Germline variants affecting the proofreading activity of polymerases epsilon and delta cause a hereditary cancer and adenomatous polyposis syndrome characterized by tumors with a high mutational burden and a specific mutational spectrum.In addition to sofia barclay sexy the implementation of multiple pieces of evidence for the c
A Comparison Between Pressure Wire and Microcatheter Measurements for Evaluating the Cerebral Venous Pressure Gradient
Introduction: A pressure gradient of over 8 mm Hg across the stenosis (usually located in the transverse-sigmoid junction) is one of the criteria for cerebral venous 173rd airborne brigade patch stenting in idiopathic intracranial hypertension (IIH) patients.The possible inaccuracy of the traditional microcatheter-based pressure measurements has be
The modes of Agrippa: On the refutation of the ground of all knowledge
The modes expounded keychron m4 by the ancient sceptics became a point of reference for those who try to prove, reach any truth or justify any belief.Due to it, this paper analyses the objections of the sceptic philosophers later to Aenesidemus and previous to Sextus Empiricus.Such objections are generally attributed to Agrippa and they imply a que